EXTRACTION OF SUPRAMOLECULAR COMPLEXES AND THEIR ACTIVITY AGAINST TUBERCULOSIS BASED ON NATURAL TRITERPENOIDS

Khurramova F. N; Sobirova F. A; Esanov R. S; Matchanov A. D

doi:10.17605/OSF.IO/5NTVG

Authors

Khurramova F. N Postgraduate of Institute of Bioorganic Chemistry named after A.S.Sadikov
Sobirova F. A Teacher of Institute of Bioorganic Chemistry named after A.S.Sadikov
Esanov R. S Teacher of Institute of Bioorganic Chemistry named after A.S.Sadikov
Matchanov A. D Teacher of Institute of Bioorganic Chemistry named after A.S.SadikovAddress: 100125 Tashkent city, Mirzo Ulugbek district, Mirzo Ulugbek avenue, 83.

DOI:

https://doi.org/10.17605/OSF.IO/5NTVG

Keywords:

: glycyrrhizinic acid, tuberculosis, isoniazid, rifampicin, pyrazinamide, ethambutol hydrochloride and levofloxacin, supramolecular complex

Abstract

Liquorice is a plant that is very popular in traditional Chinese medicine. More than 20 triterpenoids and about 300 flavonoids have been isolated from the licorice plant. Among these isolated components, 73 biologically active components have been identified and 91 of them have been used for various purposes. Studies show that the two main triterpenoids in licorice plant, Glycyrrhizin (GL) and 18b-Glycyrrhetinic acid (GA), have many pharmacological properties. For example, it can treat viruses, inflammation, tumors, bacteria, and even treat tuberculosis.

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